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Controlled Delivery of Sonic Hedgehog Morphogen and Its Potential for Cardiac Repair
The morphogen Sonic hedgehog (Shh) holds great promise for repair or regeneration of tissues suffering ischemic injury, however clinical translation is limited by its short half-life in the body. Here, we describe a coacervate delivery system which incorporates Shh, protects it from degradation, and...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653884/ https://www.ncbi.nlm.nih.gov/pubmed/23690982 http://dx.doi.org/10.1371/journal.pone.0063075 |