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P. aeruginosa Lipopolysaccharide-Induced MUC5AC and CLCA3 Expression Is Partly through Duox1 In Vitro and In Vivo

BACKGROUND: We have previously found that reactive oxygen species (ROS) are involved in Pseudomonas aeruginosa lipopolysaccharide (PA-LPS) induced MUC5AC in airway epithelial cells. Dual oxidase1 (Duox1), a member of NADPH oxidase(Nox), is known to be responsible for ROS production in respiratory tr...

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Detalles Bibliográficos
Autores principales: Li, Wen, Yan, Fugui, Zhou, Hongbin, Lin, Xiaoping, Wu, Yinfang, Chen, Ce, Zhou, Niya, Chen, Zhihua, Li, Jian-dong, Shen, Huahao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653940/
https://www.ncbi.nlm.nih.gov/pubmed/23691121
http://dx.doi.org/10.1371/journal.pone.0063945