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Dosage Transmission Disequilibrium Test (dTDT) for Linkage and Association Detection

Both linkage and association studies have been successfully applied to identify disease susceptibility genes with genetic markers such as microsatellites and Single Nucleotide Polymorphisms (SNPs). As one of the traditional family-based studies, the Transmission/Disequilibrium Test (TDT) measures th...

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Detalles Bibliográficos
Autores principales: Zhang, Zhehao, Wang, Jen-Chyong, Howells, William, Lin, Peng, Agrawal, Arpana, Edenberg, Howard J., Tischfield, Jay A., Schuckit, Marc A., Bierut, Laura J., Goate, Alison, Rice, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653954/
https://www.ncbi.nlm.nih.gov/pubmed/23691058
http://dx.doi.org/10.1371/journal.pone.0063526