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Dosage Transmission Disequilibrium Test (dTDT) for Linkage and Association Detection
Both linkage and association studies have been successfully applied to identify disease susceptibility genes with genetic markers such as microsatellites and Single Nucleotide Polymorphisms (SNPs). As one of the traditional family-based studies, the Transmission/Disequilibrium Test (TDT) measures th...
Autores principales: | Zhang, Zhehao, Wang, Jen-Chyong, Howells, William, Lin, Peng, Agrawal, Arpana, Edenberg, Howard J., Tischfield, Jay A., Schuckit, Marc A., Bierut, Laura J., Goate, Alison, Rice, John P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653954/ https://www.ncbi.nlm.nih.gov/pubmed/23691058 http://dx.doi.org/10.1371/journal.pone.0063526 |
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