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Perforin Is Detrimental to Controllinγ C. muridarum Replication In Vitro, but Not In Vivo

CD4 T cells are critical for clearing experimental Chlamydia muridarum genital tract infections. Two independent in vitro CD4 T cell mechanisms have been identified for terminating Chlamydia replication in epithelial cells. One mechanism, requiring IFN-γ and T cell-epithelial cell contact, terminate...

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Detalles Bibliográficos
Autores principales: Johnson, Raymond M., Kerr, Micah S., Slaven, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653963/
https://www.ncbi.nlm.nih.gov/pubmed/23691028
http://dx.doi.org/10.1371/journal.pone.0063340