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Perforin Is Detrimental to Controllinγ C. muridarum Replication In Vitro, but Not In Vivo
CD4 T cells are critical for clearing experimental Chlamydia muridarum genital tract infections. Two independent in vitro CD4 T cell mechanisms have been identified for terminating Chlamydia replication in epithelial cells. One mechanism, requiring IFN-γ and T cell-epithelial cell contact, terminate...
Autores principales: | Johnson, Raymond M., Kerr, Micah S., Slaven, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653963/ https://www.ncbi.nlm.nih.gov/pubmed/23691028 http://dx.doi.org/10.1371/journal.pone.0063340 |
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