Structural Basis for the Oligomerization-State Switch from a Dimer to a Trimer of an Engineered Cortexillin-1 Coiled-Coil Variant

Coiled coils are well suited to drive subunit oligomerization and are widely used in applications ranging from basic research to medicine. The optimization of these applications requires a detailed understanding of the molecular determinants that control of coiled-coil formation. Although many of th...

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Detalles Bibliográficos
Autores principales: Bjelić, Saša, Wieser, Mara, Frey, Daniel, Stirnimann, Christian U., Chance, Mark R., Jaussi, Rolf, Steinmetz, Michel O., Kammerer, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653964/
https://www.ncbi.nlm.nih.gov/pubmed/23691037
http://dx.doi.org/10.1371/journal.pone.0063370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653964/
https://www.ncbi.nlm.nih.gov/pubmed/23691037
http://dx.doi.org/10.1371/journal.pone.0063370

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