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Structural Basis for the Oligomerization-State Switch from a Dimer to a Trimer of an Engineered Cortexillin-1 Coiled-Coil Variant
Coiled coils are well suited to drive subunit oligomerization and are widely used in applications ranging from basic research to medicine. The optimization of these applications requires a detailed understanding of the molecular determinants that control of coiled-coil formation. Although many of th...
Autores principales: | Bjelić, Saša, Wieser, Mara, Frey, Daniel, Stirnimann, Christian U., Chance, Mark R., Jaussi, Rolf, Steinmetz, Michel O., Kammerer, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653964/ https://www.ncbi.nlm.nih.gov/pubmed/23691037 http://dx.doi.org/10.1371/journal.pone.0063370 |
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