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Francisella tularensis subsp. tularensis Induces a Unique Pulmonary Inflammatory Response: Role of Bacterial Gene Expression in Temporal Regulation of Host Defense Responses

Pulmonary exposure to Francisella tularensis is associated with severe lung pathology and a high mortality rate. The lack of induction of classical inflammatory mediators, including IL1-β and TNF-α, during early infection has led to the suggestion that F. tularensis evades detection by host innate i...

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Detalles Bibliográficos
Autores principales: Walters, Kathie-Anne, Olsufka, Rachael, Kuestner, Rolf E., Cho, Ji Hoon, Li, Hong, Zornetzer, Gregory A., Wang, Kai, Skerrett, Shawn J., Ozinsky, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653966/
https://www.ncbi.nlm.nih.gov/pubmed/23690939
http://dx.doi.org/10.1371/journal.pone.0062412