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Francisella tularensis subsp. tularensis Induces a Unique Pulmonary Inflammatory Response: Role of Bacterial Gene Expression in Temporal Regulation of Host Defense Responses
Pulmonary exposure to Francisella tularensis is associated with severe lung pathology and a high mortality rate. The lack of induction of classical inflammatory mediators, including IL1-β and TNF-α, during early infection has led to the suggestion that F. tularensis evades detection by host innate i...
Autores principales: | Walters, Kathie-Anne, Olsufka, Rachael, Kuestner, Rolf E., Cho, Ji Hoon, Li, Hong, Zornetzer, Gregory A., Wang, Kai, Skerrett, Shawn J., Ozinsky, Adrian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653966/ https://www.ncbi.nlm.nih.gov/pubmed/23690939 http://dx.doi.org/10.1371/journal.pone.0062412 |
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