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Antagonism of the histamine H(4) receptor reduces LPS-induced TNF production in vivo
OBJECTIVE: Antagonism of the histamine H(4) receptor (H(4)R) has been shown to be anti-inflammatory in a number of preclinical disease models, however the exact mechanisms behind this are still being uncovered. In vitro, the receptor interacts with TLR and impacts inflammatory mediator production fr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SP Birkhäuser Verlag Basel
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654183/ https://www.ncbi.nlm.nih.gov/pubmed/23532396 http://dx.doi.org/10.1007/s00011-013-0612-5 |