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Antagonism of the histamine H(4) receptor reduces LPS-induced TNF production in vivo

OBJECTIVE: Antagonism of the histamine H(4) receptor (H(4)R) has been shown to be anti-inflammatory in a number of preclinical disease models, however the exact mechanisms behind this are still being uncovered. In vitro, the receptor interacts with TLR and impacts inflammatory mediator production fr...

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Detalles Bibliográficos
Autores principales:	Cowden, Jeffery M., Yu, Fuqu, Challapalli, Mamatha, Huang, Jing-Feng, Kim, Sunhwa, Fung-Leung, Wai-Ping, Ma, Jing Ying, Riley, Jason P., Zhang, Mai, Dunford, Paul J., Thurmond, Robin L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SP Birkhäuser Verlag Basel 2013
Materias:	Original Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654183/ https://www.ncbi.nlm.nih.gov/pubmed/23532396 http://dx.doi.org/10.1007/s00011-013-0612-5

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