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Animal Models of GWAS-Identified Type 2 Diabetes Genes

More than 65 loci, encoding up to 500 different genes, have been implicated by genome-wide association studies (GWAS) as conferring an increased risk of developing type 2 diabetes (T2D). Whilst mouse models have in the past been central to understanding the mechanisms through which more penetrant ri...

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Detalles Bibliográficos
Autores principales: da Silva Xavier, Gabriela, Bellomo, Elisa A., McGinty, James A., French, Paul M., Rutter, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654344/
https://www.ncbi.nlm.nih.gov/pubmed/23710470
http://dx.doi.org/10.1155/2013/906590