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Curcumin Protects Human Keratinocytes against Inorganic Arsenite-Induced Acute Cytotoxicity through an NRF2-Dependent Mechanism

Human exposure to inorganic arsenic leads to various dermal disorders, including hyperkeratosis and skin cancer. Curcumin is demonstrated to induce remarkable antioxidant activity in a variety of cells and tissues. The present study aimed at identifying curcumin as a potent activator of nuclear fact...

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Detalles Bibliográficos
Autores principales: Zhao, Rui, Yang, Bei, Wang, Linlin, Xue, Peng, Deng, Baocheng, Zhang, Guohua, Jiang, Shukun, Zhang, Miao, Liu, Min, Pi, Jingbo, Guan, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654359/
https://www.ncbi.nlm.nih.gov/pubmed/23710286
http://dx.doi.org/10.1155/2013/412576