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Hepatic Gene Expression Profiling in Nrf2 Knockout Mice after Long-Term High-Fat Diet-Induced Obesity

Introduction. The transcription factor NFE2-related factor 2 (Nrf2) is a central regulator of antioxidant and detoxification gene expression in response to electrophilic or oxidative stress. Nrf2 has recently been shown to cross-talk with metabolic pathways, and its gene deletion protected mice from...

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Detalles Bibliográficos
Autores principales: Chartoumpekis, Dionysios V., Ziros, Panos G., Zaravinos, Apostolos, Iskrenova, Ralitsa P., Psyrogiannis, Agathoklis I., Kyriazopoulou, Venetsana E., Sykiotis, Gerasimos P., Habeos, Ioannis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654373/
https://www.ncbi.nlm.nih.gov/pubmed/23710285
http://dx.doi.org/10.1155/2013/340731