A Novel Aurora-A Inhibitor, BPR1K0609S1, Sensitizes Colorectal Tumor cells to 5-Fluorofracil (5-FU) Treatment

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Small synthetic compounds have been implicated in treatment of human cancers. We have synthesized a small compound, BPR1K0609S1 (hereafter, BP), which inhibits Aurora-A kinase. In the present study, we studied the mechanism of BP suppression of tumorigenesis induced by Aurora-A. Given our previous r...

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Detalles Bibliográficos
Autores principales: Shionome, Yoshimi, Lin, Wen-Hsing, Shiao, Hui-Yi, Hsieh, Hsing-Pang, Hsu, John Tsu-An, Ouchi, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654437/
https://www.ncbi.nlm.nih.gov/pubmed/23678290
http://dx.doi.org/10.7150/ijbs.5806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654437/
https://www.ncbi.nlm.nih.gov/pubmed/23678290
http://dx.doi.org/10.7150/ijbs.5806

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