Towards the Total Synthesis of Pl-3: Preparation of the Eastern Fragment through a Diastereoselective SmI(2)-Mediated Reformatsky Reaction

The jatrophane diterpene Pl-3, isolated in 2003 from Euphorbia platyphyllos, is a structurally complex natural product with highly promising biological properties that include pronounced antiproliferative activity and the inhibition of the efflux-pump activity of multidrug resistance p-glycoprotein....

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Detalles Bibliográficos
Autores principales: Fürst, Rita, Lentsch, Christoph, Rinner, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654569/
https://www.ncbi.nlm.nih.gov/pubmed/23687456
http://dx.doi.org/10.1002/ejoc.201300148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654569/
https://www.ncbi.nlm.nih.gov/pubmed/23687456
http://dx.doi.org/10.1002/ejoc.201300148

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