Mimotope vaccine efficacy gets a "boost" from native tumor antigens

Tumor-associated antigen (TAA)-targeting mimotope peptides exert more prominent immunostimulatory functions than unmodified TAAs, with the caveat that some T-cell clones exhibit a relatively low affinity for TAAs. Combining mimotope-based vaccines with native TAAs in a prime-boost setting significan...

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Detalles Bibliográficos
Autores principales: Buhrman, Jonathan D., Slansky, Jill E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654579/
https://www.ncbi.nlm.nih.gov/pubmed/23734309
http://dx.doi.org/10.4161/onci.23492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654579/
https://www.ncbi.nlm.nih.gov/pubmed/23734309
http://dx.doi.org/10.4161/onci.23492

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