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Mimotope vaccine efficacy gets a "boost" from native tumor antigens
Tumor-associated antigen (TAA)-targeting mimotope peptides exert more prominent immunostimulatory functions than unmodified TAAs, with the caveat that some T-cell clones exhibit a relatively low affinity for TAAs. Combining mimotope-based vaccines with native TAAs in a prime-boost setting significan...
Autores principales: | Buhrman, Jonathan D., Slansky, Jill E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654579/ https://www.ncbi.nlm.nih.gov/pubmed/23734309 http://dx.doi.org/10.4161/onci.23492 |
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