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Enhanced immunity in slowly aging mutant mice with high mitochondrial oxidative stress
The mitochondria of slowly aging Mclk1(+/−) mutant mice produce high levels of reactive oxygen species (ROS). These animals display enhanced immune reactivity in response to lipopolysaccharide, Salmonella, and tumor-cell grafts, experience limited damage from these treatments and are partially prote...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654596/ https://www.ncbi.nlm.nih.gov/pubmed/23734326 http://dx.doi.org/10.4161/onci.23793 |