The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4(+) T cells

Programmed cell death 1 ligand 1 (PD-L1) is an important regulator of T-cell responses and may consequently limit anticancer immunity. We have recently identified PD-L1-specific, cytotoxic CD8(+) T cells. In the present study, we develop these findings and report that CD4(+) helper T cells spontaneo...

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Detalles Bibliográficos
Autores principales: Munir, Shamaila, Andersen, Gitte Holmen, Svane, Inge Marie, Andersen, Mads Hald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654604/
https://www.ncbi.nlm.nih.gov/pubmed/23734334
http://dx.doi.org/10.4161/onci.23991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654604/
https://www.ncbi.nlm.nih.gov/pubmed/23734334
http://dx.doi.org/10.4161/onci.23991

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