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The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4(+) T cells
Programmed cell death 1 ligand 1 (PD-L1) is an important regulator of T-cell responses and may consequently limit anticancer immunity. We have recently identified PD-L1-specific, cytotoxic CD8(+) T cells. In the present study, we develop these findings and report that CD4(+) helper T cells spontaneo...
Autores principales: | Munir, Shamaila, Andersen, Gitte Holmen, Svane, Inge Marie, Andersen, Mads Hald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654604/ https://www.ncbi.nlm.nih.gov/pubmed/23734334 http://dx.doi.org/10.4161/onci.23991 |
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