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NFAT Signaling in Osteoblasts Regulates the Hematopoietic Niche in the Bone Microenvironment

Osteoblasts support hematopoietic cell development, including B lymphopoiesis. We have previously shown that the nuclear factor of activated T cells (NFAT) negatively regulates osteoblast differentiation and bone formation. Interestingly, in smooth muscle, NFAT has been shown to regulate the express...

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Detalles Bibliográficos
Autores principales: Sesler, Cheryl L., Zayzafoon, Majd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654658/
https://www.ncbi.nlm.nih.gov/pubmed/24023563
http://dx.doi.org/10.1155/2013/107321