1,25-Dihydroxyvitamin D3 Inhibits the RANKL Pathway and Impacts on the Production of Pathway-Associated Cytokines in Early Rheumatoid Arthritis

Objectives. To study effects of 1,25-dihydroxyvitamin D3 (1,25(OH)(2)D(3)) on RANKL signaling pathway and pathway-associated cytokines in patients with rheumatoid arthritis (RA). Methods. Receptor activator of nuclear factor-kappa B ligand (RANKL), osteoprotegerin (OPG), IFN-γ, IL-6, TNF-α, IL-17, a...

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Detalles Bibliográficos
Autores principales: Luo, Jing, Wen, Hongyan, Guo, Hui, Cai, Qi, Li, Shuangtian, Li, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654697/
https://www.ncbi.nlm.nih.gov/pubmed/23710436
http://dx.doi.org/10.1155/2013/101805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654697/
https://www.ncbi.nlm.nih.gov/pubmed/23710436
http://dx.doi.org/10.1155/2013/101805

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