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The Phenotype of the Cryptococcus-Specific CD4(+) Memory T-Cell Response Is Associated With Disease Severity and Outcome in HIV-Associated Cryptococcal Meningitis
Background. Correlates of immune protection in patients with human immunodeficiency virus (HIV)–associated cryptococcal meningitis are poorly defined. A clearer understanding of these immune responses is essential to inform rational development of immunotherapies. Methods. Cryptococcal-specific peri...
Autores principales: | Jarvis, Joseph N., Casazza, Joseph P., Stone, Hunter H., Meintjes, Graeme, Lawn, Stephen D., Levitz, Stuart M., Harrison, Thomas S., Koup, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654748/ https://www.ncbi.nlm.nih.gov/pubmed/23493728 http://dx.doi.org/10.1093/infdis/jit099 |
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