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Novel epithelial cell adhesion molecule antibody conjugated polyethyleneimine-capped gold nanoparticles for enhanced and targeted small interfering RNA delivery to retinoblastoma cells

BACKGROUND: Several nanoconjugates have been designed to deliver nucleic acids such as small interfering RNA (siRNA) and DNA to cells to study silencing and expression efficacies. In the present study, we prepared novel epithelial cell adhesion molecule (EpCAM) monoclonal antibody conjugated polyeth...

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Detalles Bibliográficos
Autores principales: Mitra, Moutushy, Kandalam, Mallikarjuna, Rangasamy, Judith, Shankar, Balaji, Maheswari, Uma K., Swaminathan, Sethuraman, Krishnakumar, Subramanian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654846/
https://www.ncbi.nlm.nih.gov/pubmed/23687439