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Integrating peptides' sequence and energy of contact residues information improves prediction of peptide and HLA-I binding with unknown alleles
BACKGROUND: The HLA (human leukocyte antigen) class I is a kind of molecule encoded by a large family of genes and is characteristic of high polymorphism. Now the number of the registered HLA-I molecules has exceeded 3000. Slight differences in the amino acid sequences of HLAs would make them bind t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654895/ https://www.ncbi.nlm.nih.gov/pubmed/23815611 http://dx.doi.org/10.1186/1471-2105-14-S8-S1 |