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Distinct position-specific sequence features of hexa-peptides that form amyloid-fibrils: application to discriminate between amyloid fibril and amorphous β-aggregate forming peptide sequences

BACKGROUND: Comparison of short peptides which form amyloid-fibrils with their homologues that may form amorphous β-aggregates but not fibrils, can aid development of novel amyloid-containing nanomaterials with well defined morphologies and characteristics. The knowledge gained from the comparative...

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Detalles Bibliográficos
Autores principales: Thangakani, A Mary, Kumar, Sandeep, Velmurugan, D, Gromiha, M Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654898/
https://www.ncbi.nlm.nih.gov/pubmed/23815227
http://dx.doi.org/10.1186/1471-2105-14-S8-S6