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WAVE2 Regulates Epithelial Morphology and Cadherin Isoform Switching through Regulation of Twist and Abl

BACKGROUND: Epithelial morphogenesis is a dynamic process that involves coordination of signaling and actin cytoskeletal rearrangements. PRINCIPAL FINDINGS: We analyzed the contribution of the branched actin regulator WAVE2 in the development of 3-dimensional (3D) epithelial structures. WAVE2-knockd...

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Detalles Bibliográficos
Autores principales: Bryce, Nicole S., Reynolds, Albert B., Koleske, Anthony J., Weaver, Alissa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654908/
https://www.ncbi.nlm.nih.gov/pubmed/23691243
http://dx.doi.org/10.1371/journal.pone.0064533