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5′ tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction

BACKGROUND: Small RNAs complex with proteins to mediate a variety of functions in animals and plants. Some small RNAs, particularly miRNAs, circulate in mammalian blood and may carry out a signaling function by entering target cells and modulating gene expression. The subject of this study is a set...

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Detalles Bibliográficos
Autores principales: Dhahbi, Joseph M, Spindler, Stephen R, Atamna, Hani, Yamakawa, Amy, Boffelli, Dario, Mote, Patricia, Martin, David IK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654920/
https://www.ncbi.nlm.nih.gov/pubmed/23638709
http://dx.doi.org/10.1186/1471-2164-14-298