Peroxisome Proliferator-Activated Receptor δ Agonist, HPP593, Prevents Renal Necrosis under Chronic Ischemia

The Goldblatt’s 2 kidney 1 clip (2K1C) rat animal model of renovascular hypertension is characterized by ischemic nephropathy of the clipped kidney. 2K1C rats were treated with a specific peroxisome proliferator-activated receptor δ (PPARδ) agonist, HPP593. Clipped kidneys from untreated rats develo...

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Detalles Bibliográficos
Autores principales: Fedorova, Larisa V., Sodhi, Komal, Gatto-Weis, Cara, Puri, Nitin, Hinds, Terry D., Shapiro, Joseph I., Malhotra, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654981/
https://www.ncbi.nlm.nih.gov/pubmed/23691217
http://dx.doi.org/10.1371/journal.pone.0064436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654981/
https://www.ncbi.nlm.nih.gov/pubmed/23691217
http://dx.doi.org/10.1371/journal.pone.0064436

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