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Discovering putative prion sequences in complete proteomes using probabilistic representations of Q/N-rich domains
BACKGROUND: Prion proteins conform a special class among amyloids due to their ability to transmit aggregative folds. Prions are known to act as infectious agents in neurodegenerative diseases in animals, or as key elements in transcription and translation processes in yeast. It has been suggested t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654983/ https://www.ncbi.nlm.nih.gov/pubmed/23663289 http://dx.doi.org/10.1186/1471-2164-14-316 |