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Reconstruction of the biosynthetic pathway for the core fungal polyketide scaffold rubrofusarin in Saccharomyces cerevisiae

BACKGROUND: Fungal polyketides include commercially important pharmaceuticals and food additives, e.g. the cholesterol-lowering statins and the red and orange monascus pigments. Presently, production relies on isolation of the compounds from the natural producers, and systems for heterologous produc...

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Detalles Bibliográficos
Autores principales: Rugbjerg, Peter, Naesby, Michael, Mortensen, Uffe H, Frandsen, Rasmus JN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654996/
https://www.ncbi.nlm.nih.gov/pubmed/23557488
http://dx.doi.org/10.1186/1475-2859-12-31