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Reconstruction of the biosynthetic pathway for the core fungal polyketide scaffold rubrofusarin in Saccharomyces cerevisiae
BACKGROUND: Fungal polyketides include commercially important pharmaceuticals and food additives, e.g. the cholesterol-lowering statins and the red and orange monascus pigments. Presently, production relies on isolation of the compounds from the natural producers, and systems for heterologous produc...
Autores principales: | Rugbjerg, Peter, Naesby, Michael, Mortensen, Uffe H, Frandsen, Rasmus JN |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654996/ https://www.ncbi.nlm.nih.gov/pubmed/23557488 http://dx.doi.org/10.1186/1475-2859-12-31 |
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