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Silencing of Nicotiana benthamiana Neuroblastoma-Amplified Gene causes ER stress and cell death

BACKGROUND: Neuroblastoma Amplified Gene (NAG) was identified as a gene co-amplified with the N-myc gene, whose genomic amplification correlates with poor prognosis of neuroblastoma. Later it was found that NAG is localized in endoplasmic reticulum (ER) and is a component of the syntaxin 18 complex...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Yong, Sarowar, Sujon, Kim, Hee Seung, Kim, Hyeran, Hwang, Inhwan, Kim, Young Jin, Pai, Hyun-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654999/
https://www.ncbi.nlm.nih.gov/pubmed/23621803
http://dx.doi.org/10.1186/1471-2229-13-69