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Vincristine could partly suppress stromal support to T-ALL blasts during pegylated arginase I treatment
BACKGROUND: Relapsed T-lineage acute lymphoblastic leukemia (T-ALL) has been an incurable disease. Recent reports showed that an L-arginine depleting enzyme, pegylated arginase (BCT-100) may be effective against T-ALL cells. On the other hand, studies including ours had shown the symbiosis of ALL bl...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655039/ https://www.ncbi.nlm.nih.gov/pubmed/23574711 http://dx.doi.org/10.1186/2162-3619-2-11 |