Lack of Genotoxicity due to Foamy Virus Vector Integration in Human iPSCs

Integrating vectors can lead to the dysregulation of nearby chromosomal genes, with important consequences for clinical trials and cellular engineering. This includes the retroviral and lentiviral vectors commonly used for deriving induced pluripotent stem cells (iPSCs). We previously used integrati...

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Detalles Bibliográficos
Autores principales: Deyle, David R., Khan, Iram F., Ren, Gaoying, Russell, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655141/
https://www.ncbi.nlm.nih.gov/pubmed/23388702
http://dx.doi.org/10.1038/gt.2013.6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655141/
https://www.ncbi.nlm.nih.gov/pubmed/23388702
http://dx.doi.org/10.1038/gt.2013.6

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