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Lack of Genotoxicity due to Foamy Virus Vector Integration in Human iPSCs
Integrating vectors can lead to the dysregulation of nearby chromosomal genes, with important consequences for clinical trials and cellular engineering. This includes the retroviral and lentiviral vectors commonly used for deriving induced pluripotent stem cells (iPSCs). We previously used integrati...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655141/ https://www.ncbi.nlm.nih.gov/pubmed/23388702 http://dx.doi.org/10.1038/gt.2013.6 |