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Gold Nanoparticle Delivery of Modified CpG Stimulates Macrophages and Inhibits Tumor Growth for Enhanced Immunotherapy

Gold nanoparticle accumulation in immune cells has commonly been viewed as a side effect for cancer therapeutic delivery; however, this phenomenon can be utilized for developing gold nanoparticle mediated immunotherapy. Here, we conjugated a modified CpG oligodeoxynucleotide immune stimulant to gold...

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Detalles Bibliográficos
Autores principales: Lin, Adam Yuh, Mattos Almeida, Joao Paulo, Bear, Adham, Liu, Nathan, Luo, Laureen, Foster, Aaron Edward, Drezek, Rebekah Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655178/
https://www.ncbi.nlm.nih.gov/pubmed/23691064
http://dx.doi.org/10.1371/journal.pone.0063550