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The Role of the Hippo Pathway in Melanocytes and Melanoma

The Hippo signaling pathway comprises a series of cytoplasmic tumor suppressor proteins including Merlin and the Lats1/2 and MST1/2 kinases, and is thought to play a critical role in determining the sizes of organs and tissues. The Hippo pathway is regulated upstream by extracellular mechanosensory...

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Detalles Bibliográficos
Autores principales: Kim, Ji Eun, Finlay, Graeme J., Baguley, Bruce C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655322/
https://www.ncbi.nlm.nih.gov/pubmed/23720711
http://dx.doi.org/10.3389/fonc.2013.00123