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The Role of the Hippo Pathway in Melanocytes and Melanoma
The Hippo signaling pathway comprises a series of cytoplasmic tumor suppressor proteins including Merlin and the Lats1/2 and MST1/2 kinases, and is thought to play a critical role in determining the sizes of organs and tissues. The Hippo pathway is regulated upstream by extracellular mechanosensory...
Autores principales: | Kim, Ji Eun, Finlay, Graeme J., Baguley, Bruce C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655322/ https://www.ncbi.nlm.nih.gov/pubmed/23720711 http://dx.doi.org/10.3389/fonc.2013.00123 |
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