Distinct ERG rearrangement prevalence in prostate cancer: higher frequency in young age and in low PSA prostate cancer

BACKGROUND: The TMPRSS2-ERG gene fusion resulting in ERG overexpression has been found in around 50% of prostate cancers (PCa) and is a very early event in tumorigenesis. Most studies have reported on selected surgical cohorts with inconsistent results. We hypothesized that ERG gene rearrangements i...

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Detalles Bibliográficos
Autores principales: Schaefer, G, Mosquera, J-M, Ramoner, R, Park, K, Romanel, A, Steiner, E, Horninger, W, Bektic, J, Ladurner-Rennau, M, Rubin, M A, Demichelis, F, Klocker, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655380/
https://www.ncbi.nlm.nih.gov/pubmed/23381693
http://dx.doi.org/10.1038/pcan.2013.4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655380/
https://www.ncbi.nlm.nih.gov/pubmed/23381693
http://dx.doi.org/10.1038/pcan.2013.4

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