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Distinct ERG rearrangement prevalence in prostate cancer: higher frequency in young age and in low PSA prostate cancer
BACKGROUND: The TMPRSS2-ERG gene fusion resulting in ERG overexpression has been found in around 50% of prostate cancers (PCa) and is a very early event in tumorigenesis. Most studies have reported on selected surgical cohorts with inconsistent results. We hypothesized that ERG gene rearrangements i...
Autores principales: | Schaefer, G, Mosquera, J-M, Ramoner, R, Park, K, Romanel, A, Steiner, E, Horninger, W, Bektic, J, Ladurner-Rennau, M, Rubin, M A, Demichelis, F, Klocker, H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655380/ https://www.ncbi.nlm.nih.gov/pubmed/23381693 http://dx.doi.org/10.1038/pcan.2013.4 |
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