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Transcription-coupled eviction of histones H2A/H2B governs V(D)J recombination

Initiation of V(D)J recombination critically relies on the formation of an accessible chromatin structure at recombination signal sequences (RSSs) but how this accessibility is generated is poorly understood. Immunoglobulin light-chain loci normally undergo recombination in pre-B cells. We show here...

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Detalles Bibliográficos
Autores principales: Bevington, Sarah, Boyes, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655464/
https://www.ncbi.nlm.nih.gov/pubmed/23463099
http://dx.doi.org/10.1038/emboj.2013.42