Transient neuromotor phenotype in transgenic spastic mice expressing low levels of glycine receptor β-subunit: an animal model of startle disease

Startle disease or hereditary hyperekplexia has been shown to result from mutations in the α(1)-subunit gene of the inhibitory glycine receptor (GlyR). In hyperekplexia patients, neuromotor symptoms generally become apparent at birth, improve with age, and often disappear in adulthood. Loss-of-funct...

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Detalles Bibliográficos
Autores principales: Becker, Lore, Hartenstein, Bettina, Schenkel, Johannes, Kuhse, Jochen, Betz, Heinrich, Weiher, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Ltd 2000
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655541/
https://www.ncbi.nlm.nih.gov/pubmed/10651857
http://dx.doi.org/10.1046/j.1460-9568.2000.00877.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655541/
https://www.ncbi.nlm.nih.gov/pubmed/10651857
http://dx.doi.org/10.1046/j.1460-9568.2000.00877.x

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