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Thermodynamic and Structural Analysis of DNA Damage Architectures Related to Replication

Damaged DNA, generated by the abstraction of one of five hydrogen atoms from the 2′-deoxyribose ring of the nucleic acid, can contain a variety of lesions, some of which compromise physiological processes. Recently, DNA damage, resulting from the formation of a C3′-thymidinyl radical in DNA oligomer...

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Detalles Bibliográficos
Autores principales: Amato, Nicholas J., Mwai, Christopher N., Mueser, Timothy C., Bryant-Friedrich, Amanda C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655575/
https://www.ncbi.nlm.nih.gov/pubmed/23710336
http://dx.doi.org/10.1155/2013/867957