Inhibitory Effects of Baicalin on the Expression and Activity of CYP3A Induce the Pharmacokinetic Changes of Midazolam in Rats

Baicalin, a flavonoid compound isolated from Scutellaria baicalensis, has been shown to possess antiinflammatory, antiviral, antitumour, and immune regulatory properties. The present study evaluated the potential herb-drug interaction between baicalin and midazolam in rats. Coadministration of a sin...

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Detalles Bibliográficos
Autores principales: Tian, Xin, Cheng, Zhen-Yu, Jin, Han, Gao, Jie, Qiao, Hai-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655607/
https://www.ncbi.nlm.nih.gov/pubmed/23710212
http://dx.doi.org/10.1155/2013/179643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655607/
https://www.ncbi.nlm.nih.gov/pubmed/23710212
http://dx.doi.org/10.1155/2013/179643

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