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Inhibitory Effects of Baicalin on the Expression and Activity of CYP3A Induce the Pharmacokinetic Changes of Midazolam in Rats

Baicalin, a flavonoid compound isolated from Scutellaria baicalensis, has been shown to possess antiinflammatory, antiviral, antitumour, and immune regulatory properties. The present study evaluated the potential herb-drug interaction between baicalin and midazolam in rats. Coadministration of a sin...

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Detalles Bibliográficos
Autores principales:	Tian, Xin, Cheng, Zhen-Yu, Jin, Han, Gao, Jie, Qiao, Hai-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655607/ https://www.ncbi.nlm.nih.gov/pubmed/23710212 http://dx.doi.org/10.1155/2013/179643

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