A short carboxyl-terminal tail is required for single-stranded DNA binding, higher-order structural organization, and stability of the mitochondrial single-stranded annealing protein Mgm101

Mgm101 is a Rad52-type single-stranded annealing protein (SSAP) required for mitochondrial DNA (mtDNA) repair and maintenance. Structurally, Mgm101 forms large oligomeric rings. Here we determine the function(s) of a 32–amino acid carboxyl-terminal tail (Mgm101(238–269)) conserved in the Mgm101 fami...

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Detalles Bibliográficos
Autores principales: Mbantenkhu, MacMillan, Wierzbicki, Sara, Wang, Xiaowen, Guo, Shangdong, Wilkens, Stephan, Chen, Xin Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655812/
https://www.ncbi.nlm.nih.gov/pubmed/23536705
http://dx.doi.org/10.1091/mbc.E13-01-0006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655812/
https://www.ncbi.nlm.nih.gov/pubmed/23536705
http://dx.doi.org/10.1091/mbc.E13-01-0006

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