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A short carboxyl-terminal tail is required for single-stranded DNA binding, higher-order structural organization, and stability of the mitochondrial single-stranded annealing protein Mgm101
Mgm101 is a Rad52-type single-stranded annealing protein (SSAP) required for mitochondrial DNA (mtDNA) repair and maintenance. Structurally, Mgm101 forms large oligomeric rings. Here we determine the function(s) of a 32–amino acid carboxyl-terminal tail (Mgm101(238–269)) conserved in the Mgm101 fami...
Autores principales: | Mbantenkhu, MacMillan, Wierzbicki, Sara, Wang, Xiaowen, Guo, Shangdong, Wilkens, Stephan, Chen, Xin Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655812/ https://www.ncbi.nlm.nih.gov/pubmed/23536705 http://dx.doi.org/10.1091/mbc.E13-01-0006 |
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